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Strategies to Minimize Regain If You Stop If you do need to stop GLP-1 treatment whether due to cost, side effects, pregnancy, or another reason these evidence-based strategies can help preserve your results as much as possible
In response to the hypothyroid state, a compensatory increase in the discharge of central hypothalamic thyrotropin-releasing hormone results in increased stimulation of prolactin secretion.2 Furthermore, prolactin elimination from the systemic circulation is reduced, which contributes to increased prolactin concentrations.2 Primary hypothyroidism can be associated with diffuse pituitary enlargement, which will reverse with appropriate thyroid hormone replacement therapy.2 Pituitary tumours Pituitary tumours are common neoplasms that exhibit a wide range of biological behaviour, as evidenced by hormonal and proliferative activities.2 Among pituitary adenomas, prolactin-producing pituitary tumours are the most common type
Diabetes (2002) 51(8):24205
Approximately two-thirds of weight loss was fat mass, with one-third coming from lean tissue
Wang et al., 2025c)
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